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UTIs are the greatest challenge for IC users

UTIs are a heavy burden for IC users and residual urine from incomplete bladder emptying is an important UTI risk factor1-4   

Luja shows enhanced performance in emptying the bladder

In a controlled crossover study, 42 adult male CIC users were randomised for a health care professional-led catheterisation with Luja and a conventional eyelet catheter (CEC) in two individual test visits. The study compared the number of flow-stops and the residual urine at first flow-stop as co-primary endpoints.

The study found Luja had

  • Significantly reduced mucosal suction compared to the CEC9
  • Significantly less residual urine compared to the CEC at first flow stop9

No adverse events were observed in this study.

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*Luja has close to no flow stops and complete bladder emptying is defined as <10 mL (NCT05485922, N=42). Individual results may vary. 
**Compared to uncoated catheters 
†Residual urine and microtrauma are UTI risk factors (Kennelly M., et al (2019), 10.1155/2019/2757862) 
 ‡ Coloplast Data-on-File, Luja Male User Product Evaluation, 2023, n=816 (63/73 new users), NL, DK, CH, FI. 

  1. Kennelly M, Thiruchelvam N, Averbeck MA, et al. Adult Neurogenic Lower Urinary Tract Dysfunction and Intermittent Catheterisation in a Community Setting: Risk Factors Model for Urinary Tract Infections. Adv Urol. 2019;2019:2757862. "Bladder emptying methods and residual urine were determined as clear risk factors”
  2. Vasudeva P, Madersbacher H. Factors implicated in pathogenesis of urinary tract infections in neurogenic bladders: some revered, few forgotten, others ignored. Neurourol Urodyn. 2014;33(1):95-100. “Postvoid residual urine (PVRU). Voiding is a protective mechanism against UTI”
  3. Grabe MB, Johansen T, Botto H, et al. Guidelines on urological infections. EAU Guidelines Presented at the 26th EAU Annual Congress, Vienna. 2013:78-93.
  4. Vahr S, Cobussen-Boekhorst H, Eikenboom J, et. Catheterisation Urethral Intermittent in Adults. Arnhem, Netherlands: European Association of Urology Nurses (EAUN); 2013. “In case of post voiding residual urine (PVR) IC once daily is recommended to prevent CAUTI”
  5. Islamoska S, Landauro MH, Zeeberg R, et al. Patient-reported risk factors for urinary tract infections are associated with lower quality of life among users of clean intermittent catheterisation. BAUN; Edinburgh 2022.
  6. Vaabengaard R, Zeeberg R, Zupet N, Bagger M, Nalbandian MT. Dependence on urinary intermittent catheterisation elicits considerable worry about urinary tract infections. INUS; Athens, Greece 2023.
  7. Averbeck MA, Kennelly M, Thiruchelvam N, Konstantinidis C, Chartier-Kastler E, Krassioukov A, Landauro M, Jacobsen L, Vaabengaard R, Islamoska S. Risk factors for urinary tract infections associated with lower quality of life among intermittent catheter users. British Journal of Nursing. 2023 Oct 12;32(18):S8-16.
  8. Landauro MH, Jacobsen L, Nascimento OF, Vaabengaard R, Thiruchelvam N and Bagi P. A multi-centre randomised controlled study confirming the improved performance with a new Micro-hole zone catheter in a population of adult male intermittent catheter users. INUS Congress; Athens, Greece 2023.
  9. Landauro MH, Jacobsen L, Tentor F, Pedersen T, Rovsing C , Feix do Nascimento O, Kennelly M. New Intermittent Urinary Micro-Hole Zone Catheter Shows Enhanced Performance in Emptying the Bladder: A Randomised, Controlled Crossover Study. J. Clin. Med. 2023, 12, 5266. https://doi.org/10.3390/jcm12165266
  10. Stensballe J, Looms D, Nielsen PN, et al. Hydrophilic-coated catheters for intermittent catheterisation reduce urethral micro trauma: a prospective, randomised, participant-blinded, crossover study of three different types of catheters. Eur Urol. 2005;48(6):978-83.
  11. De Ridder DJ, Everaert K, Fernández LG, et al. Intermittent catheterisation with hydrophilic-coated catheters (SpeediCath) reduces the risk of clinical urinary tract infection in spinal cord injured patients: a prospective randomised parallel comparative trial. Eur Urol. 2005;48(6):991-5.
  12. Cardenas DD, Moore KN, Dannels-McClure A, et al. Intermittent catheterization with a hydrophilic-coated catheter delays urinary tract infections in acute spinal cord injury: a prospective, randomized, multicenter trial. Pm r. 2011;3(5):408-17.
  13. R. Vaabengaard, S. Islamoska, R. Zeeberg, L. Jacobsen. Users of intermittent catheters feel more confidence and less worries of bladder emptying and urinary tract infections when using the Micro-hole Zone catheter Luja™. Poster no. 19 at BAUN 2023. PM-29473.